Local Anesthetic Toxicity Training: Rapid Response to a Rare but Serious Complication

Chris Hoey

September 10, 2025

Local anesthetics are among the most widely used medications in healthcare, allowing procedures to be performed safely and comfortably. But while complications are rare, systemic toxicity—known as Local Anesthetic Systemic Toxicity (LAST)—can be life-threatening if not recognized and treated immediately.

This training video covers:

  • The signs and symptoms of local anesthetic toxicity, from early neurologic changes to cardiovascular collapse.

  • Immediate steps for treatment, including airway management, seizure control, and lipid emulsion therapy.

Because LAST can progress rapidly, staff readiness is essential. Early recognition and swift intervention can prevent severe complications and save lives. This training reinforces the knowledge and confidence needed to respond effectively in critical moments.

By completing this training, your team strengthens its preparedness for a high-stakes emergency—ensuring patient safety remains the top priority.

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